I'm ASSUMING a 132" belt will last approximately twice as long as a 72" belt in the same width, give or take. So if you can find 132" belts in the type you need for less than twice the price of a 72" belt, I suppose you could save some money running a longer belt. Dedicated setups are nice too, especially if you're doing production style work.
Now, if there's no disparity between the price per inch of each length of belt, and you can find a similar quality 2x72 for a similar price, I'd probably just go with a 2x72. You'll probably REALLY save some space, and you won't have to worry about finding belts.
Again, depends on what the machine and the belts are going to cost you, and of course, what condition its in.