This is my take and no idea if it helps or not.
Not sure if this would be possible, but I think the final package would come out better if you did a custom aluminum, G10, CF, or ti scale that is designed for wood inlays in a fashion such as the standard inlay Sebenza with the two slim pieces of wood or the old Annual Sebenza with a wood inlay that covers the entire side of the handle. Something like 3M's VHB tape is what bonds the ti to wood. The Sebenza does this because it makes the knife slimmer and still allows the robust titanium to be on the handle.
A full wooden handle in this case may have some structural issues and present some challenges in terms of long-term wear if there arent supportive liners and the wood itself is made to stay thin. Staying thin would be difficult. Someone such as Ryan is making very high-quality handles out of a variety of materials. They look really good and work exceptionally well. One of these models with the front liner machines for a wooden inlay on the dominant side would look spectacular, and last forever. G10, ti, CF, and aluminum are all good candidates for this because of how strong and durable these materials are.
Another wood inlay look you may like is how the Benchmade 705BW does it (my favorite knife). It would be a little more tricky here given the handle is not flat, but not impossible. The interesting thing about this inlay is that it can be changed pretty easily. Benchmade later used this inlay fashion on multiple 707's, such as the 707 M390 blue with a CF inlay.
The other advantage I see to an inlay is that G10, aluminum, and titanium are very durable and can be cleaned up using a variety of methods (ex: sandblast titanium back to 100% cosmetic finish). Thinner wood such as what would need to be used on this handle would have more limited options for cosmetic finishing. If the wood is damaged or beaten up badly, replacement is much easier with an inlay versus having to have new liner/drill/lock fitting/spacer-standoff fitment/etc.
Ryan's CF 940 handle with a nice wood inlay like Walnut or Chestnut would me IMHO one of the prettiest mods in BM history. If you did that, I think your knife would become a Google celebrity as people would be sharing it like crazy.