its a good idea to rotate them every few months, at least, just to be safe.
that said i have had 3 SIG P220 mags loaded, all the way, 8 rounds, stuck them (w/the pistol) in my safe when i "retired" the SIG and went to glock, was gonna go shoot it/etc, and never did, took it out and shot it w/out a problem. had federal hydra shok 230 gr in it.
also keep my mossberg 500 12 gauge loaded all the way (6 rounds) forever, and the spring is the same now as when i got it. i occasionally unload, dissassemble,clean, reload, but it stays loaded.
if its a good high quality firearm, with good ammo, i dont think ya will have a problem imho. actually i think the ammo would go bad before the spring would, IIRC the nickle cased ammo in the SIG was getting discolored some, if that matters. maybe if ya left the thing in your trunk in the heat it would degrade the ammo faster?? if i had it in the trunk i would check more often i know that.
but no i wouldnt worry too much about it
greg