Standoffs for electronic equipment can be purchased through electronics distributors such as Digikey (
www.digikey.com, 1 800 344 4539) that will serve the retail market. Look on page 1009 of their catalog or go to their website, click on "catalog", "hardware --- jumpers" then "spacers/standoffs 1008 - 1011". Do not use the nylon ones, they are quite soft and will strip out. The aluminum ones are also fairly soft and may strip out. the zinc-plated brass ones are OK. Digikey does not sell ones made from steel, but they are the strongest and are more likely to be available only in large quantities (say 10000 pieces) on a special order. Digikey sells the round, zinc-plated brass ones in packs of 10 ($2.62 - $3.74) or 100 ($22.56 - $32.13) for the 1/4 inch to 1/2 inch long ones. Buy the larger quantities once you are sure which one you want since the shipping/handling ($5 for Digikey) may be more than your parts.
The shortest that Digikey sells is 1/4 inch long and would allow only 4 threads for each 6-32 screw, if the two screws touched in the middle and the spacer was centered on the two screws. Probably better to use either 4-40 screw or a longer spacer. If your handle is so thin that you cannot accomodate longer spacers, or even a 1/4 inch long one, then you probably have such a small knife that it would be hard to put enough stress on it to strip out the few threads that you have engaged. Drill the hole in your tang, and any recesses in your scales, a bit bigger (say 1/32 inch) than the diameter of the standoff. I have seen some, at work, where the hole was not exactly in the center. Make sure that you trial fit ALL of the pieces before you put the epoxy on.
Check that the screws that you use are good quality ones. I have bought some that were really soft steel. The threads would strip out, the heads would deform or the plating flakes off quite easily. I do not recommend getting screws from electronic parts distributors, like Digikey or Radio Shack, for this reason. Go to a proper fastener distributor. I have never had a problem with stripping or deforming stainless screws or screws with allen key heads. Some of the allen head screws that I have used have rusted quite easlily though. They are the black ones sold in hobby shops to hold engines on model airplanes.
Phil