Electric heat is nearly double or more in operating costs than standard heating from oil or gas. I am going to assume that you have a central heated home with forced air. I would install a duct blower to force more heat into the bedroom. Often the bedrooms are furthest away from the furnace, and air circulation as a result is poor and these rooms stay cold. Go down to the Home Depot or building supply store and go to the furnace section and ask for a duct blower. You install them inside the warm air duct below the grill, and these pull more warm air into the room from your furnace ductwork.
If the house runs on hotwater radiators, I would check the rad and bleed any air from it as airlocks prevent this type of rad from circulating the hot water properly. Check the supply valve, it should be open fully.
Check the room for airleaks and insulation levels in the attic. Sometimes the solution is to caulk cracks around the windows and adding insulation to the attic. This is the cheapest fix of all and pays you back in lower heating bills.
Electric space heaters are a temporary measure only, not a permanent fix. The heat they provide are nice, but remember that when the electric bill comes, you will pay Mr. Edison handsomely. As a rule of thumb, one electric space heater uses as much as an entire house does. IE 1000-1500 watt space heater uses as much electricity as a home with a fridge, deep freezer, furnace motor and TV with lights on all at the same time. This is just an average figure as things like electric hotwater heaters and stoves are used intermittently.
Don't forget that electric space heaters go up like the 4th of July when things like blankets and curtains come into contact with them, so make sure you have a working smoke detector in the room you are going to use them.
At the very least I would go with the electric blanket, much cheaper than running a space heater, especially if it is a large room.