I own and have used both, and think both have their strengths and weaknesses:
The Charge TTi has outside opening, one-handed S30V PE & 420c SE blades(I'm pretty sure I'm wrong in this, but I thought it was the same stuff that Buck uses it their knives), a bit holder for screwdriver variety, great scissors, and a diamond/metal file (double sided). However, the bit holder is very stubby, and if you lose a bit, it's now a useless tool. I've found that I like dedicated drivers. There's also no awl, and I sure as heck don't need a can opener on a multi-tool that I don't take camping. The Charge TTi will also run close to, or over, 100 bones.
The first thing that you will notice about the Powerlock is that it's huge. It's longer, thicker, and noticeably heavier than that charge. And that's the main reason I don't really carry it. The extra ounces really do make a difference with belt and (especially) pocket carry. It's not so bad in a backpack, but still.
One major feature that I absolutely adore is the ability to mix and match tools. I have a SOG Powerlock 1.0, and if I wanted to add a V-Cutter, I could. Or remove the blade (which I'm not a fan of, anyway), and make it airport friendly. Not sure if I could squeeze it past the TSA, but it would be a more viable solution than if the knife was still attached.
The compound leverage is really neat, too. I guess it works, but I don't have any real way to test this. I just like watching the gears move, I guess.
Oh, and there's an awl
And the down sides? Well, it's still heavy. There are no outside accessible tools, but that's okay because I usually have a pocket knife on me. There is no diamond file option. The stock, combo edged blade is chisel ground, and of no real use to me. There's that 1/4" adapter thing that has no discernible use to me. And, most importantly, the tools are a) a pain to remove from the handle, and b) clump as if they're a group of teenage girls at Winter Formal.
It should be noted that the 1.0 has that little "see-saw" lever lock only partially locks, and that there are no washers between the tools, which may be causing this issue. The Powerlock 2.0 has piano-key locks on both handles, which effectively gives each tool its own lock, rather than everyone sharing the same mechanism. I'm not sure if that's a deal breaker for you, or if you don't mind.
It's been my experience that the Charge TTi is more of a pleasure to use, for it's form and function, it's ease of access, and its lighter weight. But, it's still my MT of choice when there are no pliers or screwdrivers nearby. Hope this helps.