Regarding the Ti-Lite 6, one of the things I love about it is that it can be easily wrist-flicked open. But I'm referring specifically to the one with zyex handles and satin finish blade. I never use the thumb studs on my manual Ti-Lite 6's, the weight of the blade and a little wrist-flick is enough to easily overcome the detent.
As for the Ti-Lite 4, that's different. I could not wrist-flick my zyex handle satin blade T4, the detent divot was too deep and crisp, and the blade too light to break the detent. I had to dramatically modify that knife so I could easily wrist-flick it.
As for the Ti-Lite 6's with black coatings or bead-blasted finishes, from my experience they don't wrist flick very easily at all due to the black coatings and rougher bead-blasted surfaces around the pivots causing greater friction than with the satin finish ones. Of course the pivot areas could be sanded and polished. Or, even easier, the single bronze phosphor pivot washers on each side could be replaced with double washers so that the washers were spinning against each other rather than spinning against the blade or liner.
Here's my custom manual Ti-Lite 6, no thumb stud. All wrist-flick

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