Poz, let's say for sake of simplicity that the knife is being optimized for defensive draws from the right side pocket.
Tip-up carry equals faster draws.
If the clip is set so that the blade wants to pivot open "towards your rear" then you've optimized it for an initial forward-grip draw. The sequence is:
1) Move right hand down and back towards pocket, slip thumb in across the body of the knife's grip.
2) You want the clip and pommel as "deep" into your palm (towards your wrist) as possible.
3) Squeezing the closed knife between thumb and palm with fingers still straight, pull the knife clear of the pocket.
4) Techniques will vary at this point, but with a heavy megafolder-class blade a simple snapopen should now work without ever touching the thumbstud. Once the blade's open, clench up with the fingers. OR, reposition the fingers partway, nail the thumbstud, finish the grip.
If the blade wants to pivot FORWARD from a tip-up setup, there's some differences:
1) Your hand needs to approach the blade in pocket "from the rear"; your thumb goes in there again but the knife's pommel needs to come up past the web of your thumb.
2) Pinch the knife between thumb and the base of your forefinger, and pull it clear.
3) You now snapopen the knife with a "downward rotary motion", sort of a "cat scratching at the door" feeling. Done right and moderately hard, the blade snaps open and points "directly down".
4) Shift it a bit into a reverse grip.
This sequence is actually a bit FASTER but it starts you out in a reverse grip which is often considered inferior to the forward grips. But NOT always, and not with all styles or against all weapons. One school of thought says that at close range, reverse grip can dominate.
My personal thinking is that as a "big but slow" type I prefer forward grips and a "distance" game plan. The Hobbit Warrior is typical of the kind of thing preferred by a smaller and/or faster guy who wants to "get inside and party at high speed".
About a year ago I described the Hobbit Warrior as a commendable attempt to build the ultimate "insider gameplan" knife, and eventually that led me to ask what a comparable full-tilt-gonzo "Outsider" knife would look like.
Jim March