The handle is wide but not too wide. However, I found that with the pocket clip in the standard tip-down carry position I had a hard time reaching into my pocket wearing standard jeans, because of its width. To rectify this all I did was invert the pocket clip to enable tip-up carry and the problem was gone. I would recommend the knife highly, it fast became my current favorite (I have over 100) and is with me everyday.
Heck, I am at university right now and my 301 is sitting in the study carrel beside me, along with my Wharcom and Cricket....