If all I had was a folder and I could get to it, I'd give it a try. I'm sure as hell not gonna go down without putting up some kind of a fight. That being said, I'd much rather have a large fixed blade to any folder in that situation.
This is, of course, assuming that you can actually get to the knife before the snake wraps you up.
This is, of course, assuming that you can actually get to the knife before the snake wraps you up.