Greetings,
I have Razor Edge honing guides, a Lansky deluxe set, and lots off other sharpeners. I find that they all have their faults. Your best bet is probably to learn to sharpen freehanded on bench stones, which of course is easier said than done.
The razor edge guides are good, but the metal on the guide wears away as you sharpen. Since I use diamond stones, I find that the guides and the blades wear at about the same rate. Therefore, I have to adjust the guide along the way to maintain the same angle I started with.
(I prefer the old Buck Honemaster 136 guides, as they are easier to attach and adjust.
http://i11.ebayimg.com/01/i/05/0c/3e/b2_1_b.JPG)
The Lansky system is good at maintaining your bevel angle, but the stones are rather small, which can make the job time consuming and tedious. I recommend getting their coarse diamond stone or their diamond kit to speed up the process. While sharpening, you need to be careful not to draw the stone completely off the blade, as the sharp corners of the stones are great for putting dings in your blade. This is a real pain when you have just finished hand sanding a blade to 600 grit or finer.
I did find that the Razor Edge Book of Sharpening was well worth what I paid for it. It is a quick read that will teach you how to get a sharp edge on knives and various other tools.
As an aside, if you are like me, you will find that it's a waste of time trying to get a fine edge on your kitchen knives, as you will invariably find your wife using the freshly sharpened blade to cut on top of ceramic plates, aluminum pans, etc.
-Chris Meyer