I'm hesitant to respond to this post because it seems like a rather naive (or joke?) question. However, perhaps I can help a little. I am a biologist and while I have not worked with wild grizzlies, I have worked with people who have. You need to know that these animals are not a joke and you can't reasonably expect to kill one with a knife. You are far better off learning to use bear spray properly and making noise to alert the bears of your presence or simply avoiding areas were they frequent if you are worried you will be in a situation were you will have to fight one off. For reference, legitimate wildlife biologist use electrified fences around their grizzly camps and 12ga shotguns with heavy slugs/.45-70/405 rifles (beyond the normal "stay far away and use technology to watch them") for safety when closely studying grizzlies. If they have to get closer such as to tag, they use tranquilizers and cages. If you really want more specific answers regarding grizzly anatomy and safety in the woods you could contact Dr. Charles Robbins of Washington State University. He's a grizzly ecologist who has worked with Alaskan wild bears, though I imagine he'll find your question quite odd.
Anyway, it may sound ridiculous, but many mammals have side dominance just like people. I believe I have read that most large predators are right "paw" dominate. I can't find any documentation, though, I'm sorry to say. If you had to fight a grizzly with a knife (which is a hard situation to imagine) then you would want to try to dodge his attacks early and stab. Your goal however is more to get him to run away than it would be to kill. As far as I am aware, the only legitimate and modern documented case of killing a grizzly with a knife is one where a hunter in Alberta was trapped between a mother and her cubs and she grabbed his left arm and he managed to stab her multiple times in the neck/back with a hunting knife and survived quite badly mauled. Here's the first link I found http://outdoornewsdaily.com/index.php/archives/546 and you can see from the article the bear didn't drop dead. He also did not have the chance to try anything else to handle the bear (play dead, get further away, shoot it, etc). As far as Ben Lilly... that's a big pill to swallow, but he supposedly had a big double edged bowie.
Good luck, I hope you never have to fight a grizzly with your knife.
Anyway, it may sound ridiculous, but many mammals have side dominance just like people. I believe I have read that most large predators are right "paw" dominate. I can't find any documentation, though, I'm sorry to say. If you had to fight a grizzly with a knife (which is a hard situation to imagine) then you would want to try to dodge his attacks early and stab. Your goal however is more to get him to run away than it would be to kill. As far as I am aware, the only legitimate and modern documented case of killing a grizzly with a knife is one where a hunter in Alberta was trapped between a mother and her cubs and she grabbed his left arm and he managed to stab her multiple times in the neck/back with a hunting knife and survived quite badly mauled. Here's the first link I found http://outdoornewsdaily.com/index.php/archives/546 and you can see from the article the bear didn't drop dead. He also did not have the chance to try anything else to handle the bear (play dead, get further away, shoot it, etc). As far as Ben Lilly... that's a big pill to swallow, but he supposedly had a big double edged bowie.
Good luck, I hope you never have to fight a grizzly with your knife.