I have my first three in hand now. They are the Para Military 2, Native 5 Salt, and Chaparral.
There is another thread here where some have mentioned having issues with the spydiehole. I don't want to discount their issues, but add another data point. Even though I have a desk job and don't have super tough hands/thumbs, I didn't find any issues with the hole openers. Though it does add a little to the height of the blade, I haven't found that to be an issue in practice and they are very easy to use without needing any modifications or chamfering, at least for me.
The PM2 is quite fidget friendly. It's very comfortable in hand. I really like the compression lock. I'm curious to witness how the Native 5 Salt handles the beach when I go next month. In the mean time, I'm hoping to get more general use from that Magnacut blade. I'm super impressed with the Chaparral, though. What an awesome little knife! I took to it almost immediately and can see it becoming one of my favorites.
Overall, I'm very glad I gave these a try. Spyderco will be another brand I start building a small collection of. The next batch are already inbound.